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An anti-androgen may target any of the production steps, or it may block the effects of the androgen on target cells. Though anti-androgenic drugs and supplements are useful in treating high testosterone, their testosterone-lowering effects can lead to problems in those who dont have pre-existing, elevated testosterone, sustanon. If you have optimal, normal, or already-low testosterone, anti-androgen drugs and supplements may cause or exacerbate low testosterone symptoms. Long-term use of anti-androgens can lead to: System Signs & Symptoms Circulation Hot flashes Sweats Central nervous system Insomnia Nervousness Mood & cognition Irritability & fatigue Reduced sense of wellbeing Reduced motivation Impaired short-term memory Depression / low self-esteem Masculinity Reduced vigor and physical strength Sexuality Reduced libido Erectile dysfunction Impaired orgasm Impaired ejaculation and reduced ejaculation volume Physical features Decreased muscle mass Abdominal obesity Loss of body hair Increased total body fat Biochemistry Decreased HDL, Increased LDL Osteoporosis Reduced red cell volume Table adapted from An Update on Anti-Androgens , Grant P, et al. Symptoms of low testosterone may include: Loss of muscle mass Increased breast size Irritability Difficulty concentrating Loss of body hair, sustanon. Do not give Androgel (Testosterone-topical) to anyone else, even if they have the same symptoms as you do, testostérone et stéroïdes anabolisants. 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